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Forxatriptan intermediate tetrabenzyl pyrophosphate 990-91-0

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Forxatriptan intermediate tetrabenzyl pyrophosphate 990-91-0

【Alias】TBPP
【Catalog Number】 AP2602
【CAS #】 990-91-0
【Molecular Formula】C28H28O7P2
【Molecular Weight】538.47
English Name : Forxatriptan intermediate tetrabenzyl pyrophosphate
CAS# : 990-91-0
产品描述
Parameters

 

Alias

TBPP

Catalog Number

AP2602

CAS #

990-91-0

Molecular Formula

C28H28O7P2

Molecular Weight

538.47

Structural Formula

威智医药

Product Introduction

CAS 990-91-0

Tetrabenzyl pyrophosphate, English name Tetrabenzyl pyrophosphate, American Chemical Abstracts Registry Number cas 990-91-0.

Tetrabenzyl pyrophosphate (cas 990-91-0) is an intermediate of fasalpitant, which is a prodrug of an aprepitant oral preparation. Frank. Fasupitan dimethylglucamine and aprepitant are known as human substance P / neurokinin 1 (NK-1) selective high affinity receptor blockers, mainly by blocking nausea and vomiting signals in the brain Novel mechanisms of action come into play. Aprepitant has very little or no affinity for serotonin (5-HT3), dopamine, and glucocorticoid receptors, and is used to treat chemotherapy-induced nausea and vomiting and postoperative nausea and vomiting.

 

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