- Active Pharmaceutical Ingredients
- 酒石酸伐尼克兰
- Aprepitant, Fosapitant Intermediates
- 福沙匹坦双葡甲胺
- 维格列汀
- 艾氟康唑
- Luliconazole Intermediate
- 钆特酸葡胺
- Succinyl Alcohol Intermediate
- Mirabillon Intermediate
- Atazanavir Intermediate
- Intermediate
- 酒石酸伐尼克兰
- 阿瑞匹坦 287930-73-8
- 阿瑞匹坦 127852-28-2
- 阿瑞匹坦 287930-75-0
- 阿瑞匹坦 200000-59-5
- 阿瑞匹坦 155742-64-6
- 阿瑞匹坦 252742-72-6
- 福沙匹坦双葡甲胺 990-91-0
- 福沙匹坦双葡甲胺 265121-01-5
- 维格列汀 207557-35-5
- 维格列汀 702-82-9
- 艾氟康唑 144230-50-2
- 艾氟康唑 133775-25-4
- 艾氟康唑 127000-90-2
- 钆特酸葡胺
- 米拉贝隆
- 卢立康唑 98873-55-3
- 卢立康唑 126534-31-4
- 硫酸阿扎那韦
- 硼替佐米 179324-87-9
- 硼替佐米 114457-94-2
- 硼替佐米 205393-22-2
- 布林佐胺
- 利伐沙 446292-08-6
- 利伐沙 446292-07-5
- 西那卡塞 1005450-55-4
- 西那卡塞 585-50-2
- Eletriptan Intermediate
- 茚达特罗 312753-53-0
- 茚达特罗 173140-90-4
- Sitagliptin Intermediate
- Fosanavir Calcium Intermediate
Popular information
Aprepitant Intermediate155742-64-6
【Catalogue Number】AP0602
【CAS #】200000-59-5
【Molecular formula】 C27H26F7NO5S
【Product Introduction】(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine P-toluenesulfonate, English name is (2R,3S)-2-[(1R)-l-[3,5-Bis(trifluoromethyl)phe-nyl]ethoxy]-3-(4-fluorophenyl)-morpholine hydrochloride, the American Chemical Abstracts Registry number is cas 200000-59-5.
N-Methylcarbonyl-2-chloroacetamidrazone
CAS 155742-64-6
Alias Aprepitant Intermediate
Catalog number AP0603
CAS # 155742-64-6
Molecular formula C4H8ClN3O2
Molecular weight 165.58
Structural formula
Product introduction
CAS 155742-64-6 methyl 2- (2-chloro-1-ethylene) hydrazide formate, English name N-Methylcarbonyl-2-chloro-acetami
drazone hydrochloride, American Chemical Abstracts Registry number cas 155742-64-6.
This product (cas 155742-64-6) is an intermediate of aprepitant. Aprepitant was the first neurokinin approved by the US FDA in 2003. (NK-1) receptor blocker, which blocks the action of substance P by binding to the NK-1 receptor (mainly present in the central nervous system and its periphery). This product can cross the blood-brain barrier and occupy the NK-1 receptor in the brain. It has selectivity and high affinity, and has a high affinity for NK. 2 and NK-3 receptor affinity is very low. At the same time, this product has a low affinity for the targets of other drugs (such as dopamine receptors, 5 HT receptors) for the treatment of chemotherapy-induced nausea and vomiting symptoms.
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