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Chemotherapy antiemetic Fosaprepitant Dimeglumine 265121-04-8

【Alias】1-deoxy-1- (methylamino) -D-glucitol [3-[[((2R, 3S) -2-[(1R) -1- [3,5-bis (trifluoromethyl) benzene Yl] ethoxy] -3- (4-fluorophenyl) -4-morpholinyl] methyl] -2,5-dihydro-5-oxo-1H-1,2,4-triazole- 1-yl] phosphonate
【Catalog number】AP0600
【CAS #】170729-80-3
【Molecular formula】C23H21F7N4O3
【Product Brief】CAS 265121-04-8 Fasopitan dimethyl glucosamine, English name Fosaprepitant Dimeglumine, American Chemical Abstracts registration number cas 265121-04-8.
English Name : Fosaprepitant Dimeglumine
CAS# : 265121-04-8
产品描述
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Fosaprepitant Dimeglumine
CAS # 265121-04-8

Alias 1-deoxy-1- (methylamino) -D-glucitol [3-[[((2R, 3S) -2-[(1R) -1- [3,5-bis (trifluoromethyl) benzene Yl] ethoxy] -3- (4-fluorophenyl) -4-morpholinyl] methyl] -2,5-dihydro-5-oxo-1H-1,2,4-triazole- 1-yl] phosphonate

Catalog number AP2601

CAS # 265121-04-8

Molecular formula C60H78F14N10O20P2

Molecular weight 1587.24

Structural formula

威智医药

Product introduction

CAS 265121-04-8 Fasopitan dimethyl glucosamine, English name Fosaprepitant Dimeglumine, American Chemical Abstracts registration number cas 265121-04-8.

Fasupitan dimethylglucamine (cas 265121-04-8) is a prodrug of an oral preparation of aprepitant, which is rapidly converted into aprepitant in the body after injection. Fasupitan dimethylglucamine and aprepitant are known as human substance P / neurokinin 1 (NK-1) selective high affinity receptor blockers, mainly by blocking nausea and vomiting signals in the brain Novel mechanisms of action come into play. Aprepitant has very little or no affinity for serotonin (5-HT3), dopamine, and glucocorticoid receptors, and is used to treat chemotherapy-induced nausea and vomiting and postoperative nausea and vomiting.

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