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Vintagliptin intermediate

【别名】利伐沙班中间体
【目录号】AP8107
【CAS #】446292-08-6
【分子式】C22H19N3O6
【产品简介】 2-[[(5S)-2-氧代-3-[4-(3-氧代-4-吗啉基)苯基]-5-噁唑烷基]甲基]-1H-异吲哚-1,3(2H)-二酮,英文名为 2-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]-methyl]-1H-isoindole-1,3(2H)-dione,美国化学文摘登记号为cas 446292-08-6。
English Name : Vintagliptin intermediate
CAS# : 207557-35-5
产品描述
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Vintagliptin intermediate

(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
CAS 207557-35-5
Alias Vinitaliptin Intermediate

Catalog number AP2705

CAS # 207557-35-5

Molecular formula C7H9ClN2O

Molecular weight 172.61

Structural formula

威智医药

Product introduction

CAS 207557-35-5 (2S) -N-chloroacetyl-2-cyanotetrahydropyrrole, the English name is (2S) -1- (Chloroacetyl) -2-

pyrrolidinecarbonitrile, U.S. Chemical Abstracts Registry No. cas 207557-35-5.

(2S) -N-chloroacetyl-2-cyanotetrahydropyrrole (CAS 207557-35-5) is an intermediate of vidagliptin. Vidagliptin is a selective, competitive, and reversible DPP_4 inhibitor. By combining with DPP-4 to form a DPP-4 complex to inhibit the activity of the enzyme, while increasing the concentration of GLP-1 and promoting the production of insulin by islet B cells, it also lowers the concentration of glucagon, thereby reducing blood glucose, and has no effect on body weight. Significant impact. This product is an oral anti-diabetic drug.

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