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Lidocaine hydrochloride injection 5ml: 0.1g

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Lidocaine hydrochloride injection 5ml: 0.1g

【Drug Name】 Generic Name: Lidocaine Hydrochloride Injection
English name:Lidocaine Hydrochloride Injection
Chinese Pinyin:Yansuan Liduokayin Zhusheye
【specification】(1)5mL:0.1g (2)20mL:0.4g
[Indications] This product is a local anesthetic and anti-arrhythmic drugs. Mainly used for infiltration anesthesia, epidural anesthesia, surface anesthesia (including mucosal anesthesia during thoracoscopy or abdominal surgery) and nerve conduction block. This product can be used for ventricular premature beats and ventricular tachycardia after acute myocardial infarction. It can also be used for digitalis poisoning, cardiac surgery, and ventricular arrhythmia caused by cardiac catheterization. This product is usually ineffective against supraventricular arrhythmias.
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Instructions for lidocaine hydrochloride injection

Please read the instructions carefully and use under the guidance of a physician

Addison's syndrome (acute cardiogenic cerebral ischemia syndrome), pre-excitation syndrome, severe heart block (Including sinus, atrioventricular, and intraventricular block) patients with veins are disabled.

【Drug Name】
Common name: Lidocaine Hydrochloride Injection
English nameLidocaine Hydrochloride Injection
Chinese PinyinYansuan Liduokayin Zhusheye

【Approval Date】:

May 18, 2007

[Date of modification]:

November 17, 2014

December 01, 2015

April 19, 2016

October 19, 2016

【Ingredients】
The main component of this product is lidocaine hydrochloride, and its chemical name is: N- (2,6-xylyl) -2- (diethylamino) acetamide hydrochloride monohydrate.
Its chemical structural formula is:
威智医药
   
Molecular formulaC14H22N2O ·HCl·H2O   

Molecular weight288.82

Accessories: sodium chloride (for injection), activated carbon (for injection).

【Character】

This product is colorless and clear liquid.

【Indications】

This product is a local anesthetic and anti-arrhythmic drugs. Mainly used for infiltration anesthesia, epidural anesthesia, surface anesthesia (including mucosal anesthesia during thoracoscopy or abdominal surgery) and nerve conduction block. This product can be used for ventricular premature beats and ventricular tachycardia after acute myocardial infarction. It can also be used for digitalis poisoning, cardiac surgery, and ventricular arrhythmia caused by cardiac catheterization. This product is usually ineffective against supraventricular arrhythmias.

【specification】15mL0.1g    220mL0.4g     

【Dosage】

  1、For anesthesia:

  (1)Adults commonly used amount:

  ①Surface anesthesia: 2% -4% solution does not exceed 100mg at a time. The dose should not exceed 4.5mg / kg (without adrenaline) or every 7mg / kg (with 1: 200000 concentration of epinephrine) at the time of injection administration.

  ②Sacral block is used for labor analgesia: use 1.0% solution, limited to 200mg.

  ③Epidural block: 1.5% -2.0% solution for thoracolumbar segment, 250-300mg.

  ④Infiltration anesthesia or intravenous block: with 0.25% -0.5% solution, 50-300mg.

  ⑤Peripheral nerve block: 1.5% solution, 250-300mg for brachial plexus (unilateral), 2% solution for dental use, 20-100mg; 1% solution for intercostal nerve (per branch), 30mg, 300mg; paracervical For infiltration, use 0.5% -1.0% solution, 100 mg each on the left and right sides; 1.0% solution for paravertebral spinal nerve block (each branch), 30-50 mg, 300 mg limit; 0.5% -1.0% solution for pudendal nerve, 100 mg each on the left and right sides .

  ⑥Sympathetic ganglion block: 1.0% solution for cervical stellate nerve, 50 mg; 1.0% solution for lumbar anesthesia, 50-100 mg.

  ⑦One-time limit, 200mg (4mg / kg) without adrenal gland, 300-350mg (6mg / kg) with adrenaline; intravenous block, maximum 4mg / kg; intravenous injection for treatment, first initial dose -2mg / kg, the maximum amount is 4mg / kg, the adult intravenous infusion is limited to 1mg per minute; repeated administration multiple times, the interval should not be shorter than 45-60 minutes.

  (2) The usual dosage of children: varies with individual, the total amount of one-time administration should not exceed 4.0-4.5mg / kg, 0.25% -0.5% solution is commonly used, and 1.0% solution is used in special cases.

  2、Anti-arrhythmia:

  (1)Commonly used amount:

  ①Intravenous injection of 1-1.5mg / kg body weight (usually 50-100mg) as the first intravenous injection for 2-3 minutes, if necessary, repeat intravenous injection 1-2 times every 5 minutes, but the total amount within 1 hour shall More than 300mg. ② Intravenous infusion is generally made up of 1-4mg / mL infusion of 5% glucose injection or administered by infusion pump. After using the load, you can continue to maintain intravenous drip at a rate of 1-4mg per minute, or intravenous drip at a rate of 0.015-0.03mg / kg body weight per minute. Elderly people, heart failure, cardiogenic shock, decreased liver blood flow, liver or kidney dysfunction should reduce the dosage to 0.5-1mg intravenously per minute. That is, intravenous injection of 0.1% solution of this product can be used, and it does not exceed 100 mg per hour.

  (2) Extreme volume: The maximum load of 4.5mg / kg body weight (or 300mg) within 1 hour of intravenous injection. The maximum maintenance dose is 4 mg per minute.

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